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Obesity news courtesy of Science Daily News

Exosomes are the missing link to insulin resistance in diabetes ... read more
September 21, 2017
Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now. In a new paper, researchers identified exosomes -- extremely small vesicles or sacs secreted from most cell types -- as the missing link.

Whole food diet may help prevent colon cancer, other chronic conditions ... read more
September 21, 2017
A diet that includes plenty of colorful vegetables and fruits may contain compounds that can stop colon cancer and inflammatory bowel diseases in pigs, according to an international team of researchers. Understanding how these compounds work on a molecular level could be an initial step toward finding treatments for people with cancer, they added.

Individualized diets for irritable bowel syndrome better than placebo ... read more
September 20, 2017
Patients with irritable bowel syndrome who follow individualized diets based on food sensitivity testing experience fewer symptoms, say researchers. Their study is among the first to provide scientific evidence for this medication-free approach to a debilitating condition.

Antibiotics following C-section among obese women reduces risk of surgical infection ... read more
September 19, 2017
Among obese women undergoing cesarean delivery, a postoperative 48-hour course of antibiotics significantly decreased the rate of surgical site infection within 30 days after delivery, according to a study.

Taking a break from dieting may improve weight loss ... read more
September 18, 2017
Avoiding continuous dieting may be the key to losing weight and keeping the kilos off, the latest research shows. Researchers showed in a randomized controlled trial, that taking a two-week break during dieting may improve weight loss.

A fat-regulating enzyme could hold the key to obesity, diabetes, cancer, other diseases ... read more
September 18, 2017
It had already been known that the enzyme known as phosphatidic acid phosphatase plays a crucial role in regulating the amount of fat in the human body. Controlling it is therefore of interest in the fight against obesity. But scientists have now found that getting rid of the enzyme entirely can increase the risk of cancer, inflammation and other ills.

The body's own fat-metabolism protects against the harmful effects of sugar ... read more
September 15, 2017
Researchers have discovered that the fat-metabolism in the cells takes place simultaneously with a detoxification of the harmful substances from the blood sugar, which can avert the damage that can in turn lead to age-related diseases such as diabetes, Alzheimer's and cancer. This indicates that we have a detoxification system which we were not previously aware of.

Decreased glucose metabolism in medial prefrontal areas is associated with nutritional status in patients with prodromal and early Alzheimer's disease ... read more
September 15, 2017
A new study shows that hypometabolism in the medial prefrontal areas is specifically associated with Alzheimer's disease-related nutritional problems, and decrease in fat mass may have a key role.

Skin patch dissolves 'love handles' in mice ... read more
September 15, 2017
Researchers have developed a medicated skin patch that can turn energy-storing white fat into energy-burning brown fat locally while raising the body's metabolism. The patch could be used to burn off pockets of unwanted fat and treat metabolic disorders like obesity and diabetes.

Biomarkers in the blood prove strong role of food for type 2 diabetes ... read more
September 14, 2017
A pioneering method has demonstrated its potential in a large study, showing that metabolic fingerprints from blood samples could render important new knowledge on the connection between food and health. The study finds that diet is one of the strongest predictors of type 2 diabetes risk in older women.

Obese inducing brain mechanism ... read more
September 14, 2017
Medical researchers have demonstrated that the protein tyrosine phosphatase receptor type J (PTPRJ) inhibits leptin signaling and that induction of PTPRJ in the hypothalamus is a cause of leptin resistance.

Body fat mass distribution: A possible explanation for lower diabetes risk associated with dairy food consumption ... read more
September 13, 2017
Scientists have examined how differences in body composition may be a possible explanation for why consumption of some dairy products may be associated with a lower risk of developing type 2 diabetes or cardiometabolic disorders.

Type 2 diabetes is a reversible condition ... read more
September 13, 2017
People with type 2 diabetes can reverse the condition through a low calorie diet.

Asthma symptoms can be improved by diet and exercise in non-obese patients ... read more
September 12, 2017
Non-obese people with asthma could reduce their symptoms and improve their quality of life through diet and exercise, according to new research.

Health benefits of olives and olive oil ... read more
September 12, 2017
A research team discovered that the olive-derived compound oleuropein helps prevent type 2 diabetes.

Why high-fiber diets do not always lead to weight loss ... read more
September 12, 2017
In the era of personalized nutrition, there might be value in getting your stool tested and your gut bacteria counted before starting on a new diet. The results can be used to predict whether a particular diet will work for you. This follows a study which shows that the increasingly popular fiber-rich 'New Nordic Diet' might not work for everyone.

Your stools reveal whether you can lose weight ... read more
September 12, 2017
Something as simple as a feces sample reveals whether you can lose weight by following dietary recommendations characterized by a high content of fruit, vegetables, fibers and whole grains, report scientists.

Body clock, gut microbiota work together to pack on the pounds, study shows ... read more
September 11, 2017
New clues have been uncovered about how gut bacteria and the body's circadian clock work together to promote body fat accumulation.

Abdominal fat a key cancer driver for postmenopausal women ... read more
September 10, 2017
Body fat distribution in the trunk is more important than body weight when it comes to cancer risk in postmenopausal women, according to a new study.

Immune cells help fat deal with environmental challenges ... read more
September 8, 2017
Immunosuppressive regulatory T-cells play an important role in the functioning of adipose tissue.

Later circadian timing of food intake is associated with increased body mass index ... read more
September 8, 2017
Investigators examine the relationships between body fat and body mass index, and the timing of food consumption, to time of day and to the body's circadian or body clock.

Mediterranean-style diet may eliminate need for reflux medications ... read more
September 7, 2017
A plant-based, Mediterranean-style diet has been shown to provide the same medical benefits for treating laryngopharyngeal reflux as popular reflux medications, according to new research.

Reducing endocannabinoid system's activity may help protect the kidney health of individuals with obesity ... read more
September 7, 2017
A new study provides insights on the mechanisms behind the development of kidney damage due to obesity. The findings point to a potential target for protecting the kidney health of individuals with obesity.

Trigger for fatty liver in obesity ... read more
September 7, 2017
Morbid obesity affects the liver: almost one-third of all adults suffer from chronic fatty liver disease, which can lead to infections and even trigger cancer. Researchers have now found a signaling pathway in cells that play an important role in the development of fatty liver disease.

Whole grains decrease colorectal cancer risk, processed meats increase the risk ... read more
September 7, 2017
Major new report finds strong evidence of links between lifestyle and colorectal cancer risk. Physical activity and whole grains lowers risk of this cancer; too much alcohol and red meat, processed meats and obesity increase the risk. An estimated 47 percent of US colorectal cancers could be prevented each year with lifestyle changes.

Health of more than half of US adults affected by obesity ... read more
September 6, 2017
Considering weight across the life course, the prevalence of obesity among adults in the US rises considerably, suggesting that the effects on population health may be even more pervasive than previously understood, according to a new study.

Late bedtime and lack of sleep lead to overweight children in China ... read more
September 6, 2017
Researchers have found that Chinese children who go to bed later and sleep less are more likely to be more overweight.

Genetic effects are influenced by lifestyle ... read more
September 6, 2017
The risk for developing obesity is influenced by our lifestyle as well as our genes. Researchers now show that our genetic risk for obesity is not static, but is influenced by our lifestyle.

Eat fat, live longer? ... read more
September 5, 2017
As more people live into their 80s and 90s, researchers have delved into the issues of health and quality of life during aging. A recent mouse study sheds light on those questions by demonstrating that a high fat, or ketogenic, diet not only increases longevity, but improves physical strength.

Physical activity can lead to difference in diet preferences between males, females ... read more
September 5, 2017
Approximately 90 percent of adult Americans fail to reach the US Department of Health guidelines for physical activity, which could be contributing to surging obesity rates. Now, new research suggests that physical activity can change diet preferences in males, but not in females -- an area that researchers say has not been thoroughly studied.

Boosting a lipid fuel makes mice less sensitive to the cold ... read more
September 5, 2017
Humans, like other animals, become more sensitive to cold with age. Now, scientists report that delivering a single dose of a nutritional supplement called L-carnitine to older mice restores a youthful ability to adapt to the cold. After treatment, they tolerate chilly conditions that would ordinarily trigger hypothermia. The supplement works by boosting levels of a newly discovered fuel source for brown fat, or “good fat”.

Adipose tissue may affect cancer development in multiple ways ... read more
September 1, 2017
Adipose tissue, or fat, may influence the development of cancer in diverse ways, depending on the type of fat and the location in the body.

Discovery may be key to obesity, Diabetes Rx ... read more
August 31, 2017
Research has demonstrated the potential of a protein to treat or prevent metabolic diseases including obesity and diabetes.

How dietary fats' impact healthy or obese adults ... read more
August 30, 2017
Metabolically healthy obese adults consuming a diet high in unsaturated fat and low in saturated fat may be able to decrease their total cholesterol by 10 points, a new study suggests. However, there was little research evidence to support current dietary recommendations that replacing saturated fat with unsaturated fat aids in weight loss, the researchers also reported.

Obesity prevention guidelines are not followed for preschool children ... read more
August 29, 2017
In a study of nearly 400 preschool children, only one child adhered to obesity prevention guidelines over the course of a single day at child care and at home.

Obese people lack cells with satiety hormones ... read more
August 29, 2017
Individuals with severe overweight have an inhibited sense of satiation -- they release fewer satiety hormones than people of normal weight. The reason: the responsible cells in the gastrointestinal tract of obese people are severely reduced. Surgical weight-loss procedures can repair this disorder.

Revisiting dietary fat guidelines? ... read more
August 29, 2017
Researchers are calling for a reconsideration of global dietary guidelines in light of new data on fat intake and cardiovascular risk and early mortality.

Eating triggers endorphin release in the brain ... read more
August 28, 2017
Researchers have revealed how eating stimulates brain's endogenous opioid system to signal pleasure and satiety.

Early weight gain in pregnancy correlates with childhood obesity, first study of its size shows ... read more
August 28, 2017
Weight gain in early pregnancy has the greatest impact on infant size at birth, according to a new study. The study is the largest ever analysis of the effect that weight gain in early pregnancy has on infant size.

Shedding consistent pounds each week linked to long-term weight loss ... read more
August 28, 2017
Those whose weights fluctuated the most during the first few weeks of a weight loss program had poorer weight loss outcomes one and two years later, compared to the men and women who lost a consistent number of pounds each week.

Heart hormones protect against obesity and insulin resistance ... read more
August 25, 2017
By fleshing out how one signaling receptor contributes to causing obesity through its activity in fatty tissue but not in muscle cells, scientists have zeroed in on an important new avenue of exploration for combating metabolic disease. More than one-third of American adults are considered to be obese, which dramatically increases their risk for developing type 2 diabetes, non-alcoholic fatty liver disease, high blood pressure, and multiple inflammatory conditions.

Enzyme produced in the liver promotes obesity, fatty liver disease and insulin resistance ... read more
August 24, 2017
In mice that are given a high-fat diet, an increased production of the enzyme DPP4 by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance.

This is how belly fat could increase your cancer risk ... read more
August 24, 2017
A new study now offers new details showing that a certain protein released from fat in the body can cause a non-cancerous cell to turn into a cancerous one. The research also found that a lower layer of abdominal fat, when compared to fat just under the skin, is the more likely culprit, releasing even more of this protein and encouraging tumor growth.

Gene therapy with BMP4 protects against weight gain and insulin resistance in mice ... read more
August 24, 2017
There was no weight gain, despite a higher energy intake, and insulin sensitivity was increased. These are the results from experiments on mice that had elevated levels of the protein BMP4 following gene therapy.

Psychotic disorders and obesity: New report shows big waistlines are to blame ... read more
August 23, 2017
A number of factors, including obesity, shorten the lifespan for those with schizophrenia by 20 years and by 10 years for those with bipolar disorder compared to the general population. In the first study to compare long-term weight gain across psychotic disorders, researchers show that expanding waistlines and the way body fat is distributed are largely to blame.

Getting fat to 'talk' again could lower blood glucose and weight ... read more
August 22, 2017
Researchers are exploring a novel approach to treating diabetes: implanting a polymer sponge into fat tissue. Their study has shown that in obese mice with symptoms resembling Type 2 diabetes, the implant reduced weight gain and blood-sugar levels -- by getting the fat to 'talk' again.

Is childhood obesity a psychological disorder? ... read more
August 22, 2017
A team of researchers used fMRI to investigate neural responses to food cues in overweight compared with lean adolescents.

Brain's self-regulation in teens at risk for obesity ... read more
August 22, 2017
In a small study that scanned the brains of teenagers while exposing them to tempting 'food cues,' researchers report that reduced activity in the brain's 'self-regulation' system may be an important early predictor of adult obesity.

Federal snack program does not yield expected impacts ... read more
August 17, 2017
A research team examined the US Department of Agriculture's Smart Snacks in School regulation. The federal mandate was intended to replace unhealthy school snacks and beverages with more wholesome options, including fruits, vegetables, and packaged treats low in fat, sugar, and sodium.

College freshmen who weighed themselves daily lost body fat ... read more
August 17, 2017
A new study found that female college-aged students who reported at least one period of daily self-weighing over a two-year study saw a drop in their body mass index.

Brain chemical NPGL controls appetite and body fat composition: Beneficial for our ancestors; potential cause of obesity pandemic ... read more
August 17, 2017
NPGL, a recently discovered protein involved in brain signalling, has been found to increase fat storage by the body – even when on a low-calorie diet.

Energy dense foods may increase cancer risk regardless of obesity status ... read more
August 17, 2017
While there is a proven link between obesity and certain types of cancer, less is known about how the ratio of energy to food weight, otherwise known as dietary energy density (DED), contributes to cancer risk. To find out, researchers looked at DED in the diets of post-menopausal women and discovered that consuming high DED foods was tied to a 10 percent increase in obesity-related cancer among normal weight women.

'Fat but fit' are at increased risk of heart disease ... read more
August 15, 2017
Carrying extra weight could raise your risk of heart attack by more than a quarter, even if you are otherwise healthy.

Almonds may help boost cholesterol clean-up crew ... read more
August 11, 2017
Eating almonds on a regular basis may help boost levels of HDL cholesterol while simultaneously improving the way it removes cholesterol from the body, according to researchers.

A metabolic pathway that feeds liver cancer ... read more
August 10, 2017
A little-studied gene may explain how some liver cancer cells obtain the nutrition they need to proliferate, according to new research.

Aging is exacerbated by alterations of stem cell circadian rhythm ... read more
August 10, 2017
Two new studies refute the scientific dogma associating aging with the loss of stem cell circadian rhythm. The studies show that during aging, stem cells continue to show rhythmic activity but reprogram their circadian functions. The team also demonstrate that a low-calorie diet delays alterations in the rhythmic functions of stem cells and slows down ageing.

Weight loss surgery's effects on bone marrow fat and bone mass ... read more
August 9, 2017
Bone marrow fat is thought to regulate bone metabolism, and high levels of marrow fat are seen in states of low bone mass, severe underweight, and diabetes.

Limiting access to fast-food restaurants unlikely to reduce obesity ... read more
August 7, 2017
Living near fast-food restaurants and supermarkets has little impact on an individual's body mass index, according to new research. The researchers used results from the largest national study ever conducted of the connection between residential environments and BMI.

Fat rats show why breast cancer may be more aggressive in patients with obesity ... read more
August 7, 2017
In an animal model of obesity and breast cancer, tumor cells in obese animals but not lean animals had especially sensitive androgen receptors, allowing these cells to magnify growth signals from the hormone testosterone.

Of mice and cheeseburgers: Experimental drug reverses obesity-related liver disease ... read more
August 3, 2017
An experimental drug protected mice from one of the many ills of our cheeseburger and milkshake-laden Western diet -- non-alcoholic fatty liver disease. The drug reversed liver inflammation, injury and scarring in animals fed a high fat, sugar and cholesterol diet. The diet was designed to replicate the Western fast food diet and recreate the features of non-alcoholic fatty liver disease found in people. The research team plans further testing to move it into human trials.


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