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Childhood Obesity
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Obesity news courtesy of Science Daily News

Pediatric obesity, depression connected in the brain ... read more
April 23, 2018
Early-life obesity and depression may be driven by shared abnormalities in brain regions that process rewards, according to researchers.

Why zero-calorie sweeteners can still lead to diabetes, obesity ... read more
April 23, 2018
Increased awareness of the health consequences of eating too much sugar has fueled a dramatic uptick in the consumption of zero-calorie artificial sweeteners in recent decades. However, new research finds sugar replacements can also cause health changes that are linked with diabetes and obesity, suggesting that switching from regular to diet soda may be a case of 'out of the frying pan, into the fire.'

Fat cells seem to remember unhealthy diet ... read more
April 20, 2018
Fat cells can be damaged in a short amount of time when they are exposed to the fatty acid palmitate or the hormone TNF-alpha through a fatty diet, a new study shows. The researchers hope this new knowledge may be used to develop new preventive strategies for diabetes.

Dogs could be more similar to humans than we thought ... read more
April 19, 2018
Dog and human gut microbiomes have more similar genes and responses to diet than we previously thought, according to a new study

Neurons derived from super-obese people respond differently to appetite hormones ... read more
April 19, 2018
Scientists have successfully generated hypothalamic-like neurons from human induced pluripotent stem cells (hiPSCs) taken from the blood and skin cells of super-obese individuals and people with a normal body weight. The researchers found that the brain cells derived from the super obese were more likely to dysregulate hormones related to feeding behavior and hunger, as well as obesity-related genes and metabolic pathways.

DOR protein deficiency favors the development of obesity ... read more
April 19, 2018
Deficiency in the protein DOR (also called TP53INP2) stimulates the generation of new adipose cells (which store fat) and leads to a less harmful kind of obesity, according to a new study.

Weight-loss surgery improves lives and saves money, study finds ... read more
April 19, 2018
A new study indicates that weight-loss surgery is cost-effective over 10 years and can save healthcare systems money over a lifetime.

The bugs in your gut could make you weak in the knees ... read more
April 19, 2018
Scientists have long thought that osteoarthritis in people who are obese was a consequence of excess wear and tear on joints, but a new study suggests that the microbiome is the culprit. The study shows that a high fat diet (like the Western diet) can alter gut microbes, increase inflammation throughout the body, and speed deterioration of joints. An interesting twist: a common dietary supplement overturned these effects in mice.

Enduring cold temperatures alters fat cell epigenetics ... read more
April 19, 2018
A new study in fat cells has revealed a molecular mechanism that controls how lifestyle choices and the external environment affect gene expression. This mechanism includes potential targets for next-generation drug discovery efforts to treat metabolic diseases including diabetes and obesity.

Leptin's neural circuit identified ... read more
April 18, 2018
Scientists have identified a neural circuit in the hypothalamus as the primary mechanism mediating the hormone leptin's anti-obesity and anti-diabetes effects and found two mechanisms underlying leptin's inhibition of appetite. The work in mice advances efforts to treat human obesity and diabetes.

Obesity linked with higher chance of developing rapid, irregular heart rate ... read more
April 18, 2018
People with obesity are more likely to develop a rapid and irregular heart rate, called atrial fibrillation, which can lead to stroke, heart failure and other complications, according to Penn State researchers. They found that people with obesity had a 40 percent higher chance of developing atrial fibrillation than people without obesity.

Why is it harder for females to gain weight? ... read more
April 18, 2018
Why is it harder for females to gain weight? A new study proposes that part of the answer may be in the brain.

People with Type 2 diabetes who eat breakfast later, more likely to have a higher BMI ... read more
April 16, 2018
Being an "evening person" is linked to higher body mass indices among people with Type 2 diabetes, and having breakfast later in the day seems to be what drives this association, according to a new article.

Maternal metabolic factors and early-onset puberty ... read more
April 16, 2018
In a study of more than 15,000 girls and their mothers maternal overweight and hyperglycemia were linked to the earlier onset of puberty in girls 6 to 11 years old. Early puberty has been linked to multiple adverse health developments as girls grow up.

Can you really be obese yet healthy? ... read more
April 12, 2018
A new paper has called for an end to the term 'healthy obesity,' due to it being misleading and flawed. The focus should instead be on conducting more in-depth research to understand causes and consequences of varying health among people with the same BMI.

Study explores carbohydrates' impact on head, neck cancers ... read more
April 12, 2018
Consuming high amounts of carbohydrates and various forms of sugar during the year prior to treatment for head and neck cancer may increase patients' risks of cancer recurrence and mortality, a new study reports. However, eating moderate amounts of fats and starchy foods such as whole grains, potatoes and legumes after treatment could have protective benefits, reducing patients' risks of disease recurrence and death.

Specific bacteria in the small intestine are crucial for fat absorption ... read more
April 11, 2018
A new study -- one of a few to concentrate on microbes in the upper gastrointestinal tract -- shows how the typical calorie-dense western diet can induce expansion of microbes that promote the digestion and absorption of high-fat foods. Over time, the steady presence of these microbes can lead to over-nutrition and obesity.

Surprising discovery: Sweet tooth gene connected with less body fat ... read more
April 11, 2018
Last year researchers discovered that a particular craving for sweet things may be determined by a genetic variation. Now the researchers have discovered that people with this genetic disposition for a sweet tooth have less body fat.

Binge-eating mice reveal obesity clues ... read more
April 9, 2018
Mice fed on a high-fat or chocolate-based diet show abnormal feeding behaviors such as snacking, bingeing and disrupted eating patterns, according to new research. The findings help to explain the behavioral triggers leading to obesity and point towards new ideas for preventing weight gain.

How fat tissue shunts energy to tumors ... read more
April 9, 2018
Researchers recently discovered that that inactivation of a protein called p62 in fat cells fuels aggressive, metastatic prostate cancer in mice. The findings suggest that mTOR inhibitors currently used to treat a wide range of cancers may have the unintended consequence of shutting down fat tissue metabolism and fueling tumor growth.

Obesity impacts liver health in kids as young as 8 years old ... read more
April 4, 2018
A new study found that weight gain, obesity can put children as young as age 8 at risk for a serious liver disease.

Timing of stress-hormone pulses controls weight gain ... read more
April 4, 2018
New research provides the first molecular understanding of why people gain weight due to chronic stress, disrupted circadian rhythms and treatment with glucocorticoid drugs: it's all in the timing of the dips and rises of a class of hormones called glucocorticoids -- predominantly the 'stress hormone' cortisol, according to a new study.

Smokers have worse diets than non-smokers ... read more
April 4, 2018
Smokers have worse quality diets than former smokers or non-smokers, according to a new study.

Sulfur amino acid restriction could amount to new dietary approach to health ... read more
April 3, 2018
The longevity and health improvements seen in animals on sulfur amino acid-restricted diets could translate to people, according to researchers who recently conducted a review of published studies. More research is needed to confirm the benefits in people, the scientists said.

Pasta can be part of a healthy diet without packing on the pounds ... read more
April 3, 2018
Carbohydrates get a lot of bad press and blame for the obesity epidemic, but a new study suggests that this negative attention may not be deserved for pasta.

Can a Mediterranean diet pattern slow aging? ... read more
March 30, 2018
A series of six articles finds new correlations between a Mediterranean diet and healthy aging outcomes -- while also underscoring the need for careful approaches to the use of data in order to measure the diet's potential benefits.

Relationship changes after bariatric surgery ... read more
March 28, 2018
Individuals who have undergone bariatric surgery have a higher probability of getting married, separating from their partner or getting divorced, according to a new study.

The connection between diet, obesity, and cancer: Nutrition experts explore the evidence ... read more
March 27, 2018
About one third of cancer cases are estimated to be linked to dietary and other modifiable risk factors, especially for obesity-related cancers such as breast, colorectal, ovarian, endometrial, kidney, gallbladder, esophageal, and pancreatic cancers.

Canada–US Free Trade Agreement (CUSFTA) increased caloric intake in Canada ... read more
March 27, 2018
A new study shows that the 1989 Canada-US Free Trade Agreement (CUSFTA) was associated with an increase in caloric availability of approximately 170 kilocalories per person per day in Canada. These findings suggest that the rise in caloric intake and obesity in Canada since the early 1990s can be partially attributed to its close trade and investment arrangements with the US.

Promising drug may stop cancer-causing gene in its tracks ... read more
March 26, 2018
Scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.

Obesity is shifting cancer to young adults ... read more
March 26, 2018
Researchers have compiled evidence from more than 100 publications to show how obesity increases risk of 13 different cancers in young adults. The meta-analysis describes how obesity has shifted certain cancers to younger age groups, and intensified cellular mechanisms promoting the diseases.

New study elucidates link between PCOS and anxiety ... read more
March 23, 2018
Maternal obesity and androgen excess induce sex-specific anxiety in the offspring, according to a study on mice. The findings may help explain why children born to mothers with polycystic ovary syndrome (PCOS) have increased risk of developing anxiety later in life.

More than 2,500 cancer cases a week could be avoided ... read more
March 23, 2018
More than 135,500 cases of cancer a year in the UK could be prevented through lifestyle changes, according to new figures.

Care providers' understanding of obesity treatment is limited ... read more
March 23, 2018
Despite the high prevalence of obesity among US adults, provision of recommended treatments for obesity remains low.

Obesity surgery linked to positive outcomes in very obese teens with diabetes ... read more
March 22, 2018
This study is the first to compare glycemic control in two groups of very obese adolescents with type 2 diabetes.

Mono-unsaturated fats from plants, not animals may reduce risk of death from heart disease and other causes ... read more
March 21, 2018
Diets rich in mono-unsaturated fats from plants may lower the risk of death from heart disease and other causes. The largest reductions in the risk of death were found when healthy fats from plant sources replaced saturated fats, trans fats and refined carbohydrates.

Belly fat promotes diabetes under orders from liver ... read more
March 21, 2018
Researchers found that obesity increases the liver's production of an enzyme that triggers inflammation in belly fat. Targeting the enzyme in the liver could present a new way to treat type 2 diabetes.

Cold can activate body's 'good' fat at a cellular level, study finds ... read more
March 21, 2018
Lower temperatures can activate the body's 'good' fat formation at a cellular level, a new study has found.

Freezing hunger-signaling nerve may help ignite weight loss ... read more
March 21, 2018
Freezing the nerve that carries hunger signals to the brain may help patients with mild-to-moderate obesity lose weight, according to a newly presented study. The treatment was determined safe and feasible in the initial pilot phase.

How obesity dulls the sense of taste ... read more
March 20, 2018
Previous studies have indicated that weight gain can reduce one's sensitivity to the taste of food. Now a new study shows that inflammation, driven by obesity, actually reduces the number of taste buds on the tongues of mice.

Parenting and personality work together to affect baby's weight gain ... read more
March 20, 2018
The more mothers use food to soothe their babies, the more weight certain babies gained, according to researchers. The effect was only seen in babies with a surgent temperament -- characterized by being more outgoing, active and drawn to new things and people, putting these children at a risk for obesity later on.

High consumption of red and processed meat linked to non-alcoholic fatty liver disease and insulin resistance ... read more
March 20, 2018
World meat consumption has increased during the last decades, and evidence is mounting that high consumption of red and mainly processed meat is unhealthy to humans and is related to chronic diseases such as cancer, type 2 diabetes, and cardiovascular disease. A new study adds non-alcoholic fatty liver disease (NAFLD) to the list.

Weight loss after stomach-narrowing surgery eases chronic knee pain ... read more
March 20, 2018
A new report finds that extremely obese people who have a band surgically strapped around their stomachs to restrict food intake not only lose weight but also suffer less from arthritic knee pain.

In children with obesity, impulsivity may be linked with greater weight loss when treated ... read more
March 19, 2018
Children with obesity may be more impulsive than those with normal weight, but during family-based behavioral treatment (FBT), the more impulsive of children with obesity may lose more weight, a new study suggests.

Fasting diets reduce important risk factor for cardiovascular disease ... read more
March 19, 2018
Intermittent energy restriction diets, such as the 5:2 diet, clears fat from the blood quicker after eating meals than daily calorie restriction diets – reducing an important risk factor for cardiovascular disease, a new study reports.

High-energy breakfast promotes weight loss ... read more
March 18, 2018
In patients with obesity and type 2 diabetes, a meal schedule that includes a high-energy breakfast promotes weight loss, improves diabetes and decreases the need for insulin, new research reports.

Consuming low-calorie sweeteners may predispose overweight individuals to diabetes ... read more
March 18, 2018
Consumption of low-calorie sweeteners could promote metabolic syndrome and predispose people to prediabetes and diabetes, particularly in individuals with obesity, a new study on human fat-derived stem cells and fat samples suggests.

Mediterranean diet is linked to higher muscle mass, bone density after menopause ... read more
March 18, 2018
The heart-healthy Mediterranean diet also appears to be good for an older woman's bones and muscles, a new study of postmenopausal women in Brazil finds.

In BRCA mutation carriers, obesity is linked with increased DNA damage ... read more
March 18, 2018
Being obese or having a higher body mass index (BMI) while carrying a BRCA (BReast CAncer gene) mutation is positively linked with higher levels of damage to the DNA in normal breast gland cells, new research suggests.

New diabetes drug may help people with obesity lose weight ... read more
March 18, 2018
A compound that mimics a naturally occurring hormone that regulates appetite may help people who have obesity but not diabetes to lose weight, a new study suggests.

Race, pre-pregnancy BMI may help predict maternal weight gain ... read more
March 18, 2018
Race and pre-pregnancy body mass index (BMI) both affect leptin and adiponectin levels, and leptin levels in mid-pregnancy may be an important predictor of weight gain during pregnancy, new research suggests.

Breastfeeding may protect high-birthweight infants from childhood obesity ... read more
March 18, 2018
Breastfeeding may protect high-birthweight infants from having overweight or obesity as children, new research suggests.

Overeating during breastfeeding may affect the health of offspring ... read more
March 18, 2018
Mothers who overeat during the period when they are breastfeeding may have children who are at increased risk of becoming obese and going through early puberty, a new study of mice suggests. Early puberty may lead to increased risk of diabetes or reproductive problems later in life, according to the research.

Experimental obesity drug prevents development of kidney stones ... read more
March 16, 2018
Scientists have found that a drug connected with fat regulation prevents the formation of kidney stones in mice. This early work opens the possibility of developing drugs which may help prevent kidney stones in at-risk individuals.

Study of nearly 300,000 people challenges the 'obesity paradox' ... read more
March 15, 2018
The idea that it might be possible to be overweight or obese but not at increased risk of heart disease, otherwise known as the 'obesity paradox', has been challenged by a study of nearly 300,000 people. The research shows that the risk of heart and blood vessel problems, such as heart attacks, strokes and high blood pressure, increases as body mass index (BMI) increases beyond a BMI of 22-23 kg/m2.

Early puberty linked with increased risk of obesity for women ... read more
March 15, 2018
Girls who start puberty earlier are more likely to be overweight as adults, finds new research.

Molecule that gives energy-burning brown fat its identity could lead to drugs for obesity ... read more
March 13, 2018
A protein found in brown fat, but not typical white fat, is key to how the energy-burning brown fat cells function.

New link between obesity and body temperature ... read more
March 12, 2018
Reduced ability to maintain body temperature in colder environments may contribute to the development of obesity in adulthood, suggests a new study.

Caloric restriction in combination with low-fat diet helps protect aging mouse brains ... read more
March 12, 2018
New research finds that a low-fat diet in combination with limited caloric consumption prevents aging-induced inflammatory activation of immune cells in the mouse brain - and that exercise is significantly less effective than caloric restriction in preventing these age-related changes. This indicates that the fat content of a diet, as well as caloric intake, are important parameters for the detrimental effects of aging on the brain.

Modulation of Fgf21 gene in early-life ameliorates adulthood diet-induced obesity ... read more
March 9, 2018
The importance of good nutrition in the early development of children has been recognized for many decades. Nutritional experiences in early life can have profound and long-lasting effects on body weight in later life. For instance, malnutrition in early life as a result of poor nutrition during pregnancy and/or the lactation period may be stored on the offspring genome as epigenetic memory and persist into adulthood, thereby increasing the susceptibility to metabolic diseases such as obesity in later life. This area of epigenetics has become one of the fastest-growing and most complex areas of biological science.

 


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