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Childhood Obesity
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Obesity news courtesy of Science Daily News

Discovery could hold the key to alleviating metabolic disease ... read more
January 13, 2022
A newly characterized fat protein could provide the missing link to explain a rare metabolic disease while offering fresh insight into common disorders such as obesity and type 2 diabetes.

Chewing to stay slim: How to savor your food better and dodge weight gain ... read more
January 12, 2022
Chewing well helps in digestion. Chewing is also known to help prevent obesity, possibly by increasing the thermic effect of food consumption. But the factors behind this heat-generating effect of chewing remain less explored. A new study has revealed that oral stimuli, which are linked with the duration of tasting liquid food in the mouth, and the duration of chewing, play a positive role in increasing energy expenditure after food intake.

New target may help protect bones as we age ... read more
January 5, 2022
Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one. They are finding that in aging bone, the mineralocorticoid receptor, better known for its role in blood pressure regulation, is a key factor in bone health.

Healthy diet in early pregnancy reduces risk of gestational diabetes ... read more
December 29, 2021
A healthy, comprehensive diet that lowers the body's inflammation reduces the risk of gestational diabetes mellitus, reveals a new study.

Substantial weight loss can reduce risk of severe COVID-19 complications, study finds ... read more
December 29, 2021
A new study shows that among patients with obesity, prior weight loss achieved with bariatric surgery was associated with a 60 percent lower risk of developing severe complications from COVID-19 infection.

For some Greenlanders, eating sugar is healthy ... read more
December 22, 2021
A genetic variation among some Greenlanders makes sugar healthy -- significantly more than for most people. According to a new study, gut bacteria and a unique diet that has nourished Greenlanders for millennia have provided them with a genetic variation that offers an incredible advantage.

How diet influences taste sensitivity and preference ... read more
December 15, 2021
What you eat influences your taste for what you might want to eat next. So claims a University of California, Riverside, study performed on fruit flies. The study offers a better understanding of neurophysiological plasticity of the taste system in flies.

Breakthrough in using CRISPR-Cas9 to target fat cells ... read more
December 15, 2021
Researchers describe a breakthrough using CRISPR-Cas9, a tool that has transformed molecular biological research, but whose use in the study of adipose tissue had been elusive.

Overweight children are developing heart complications ... read more
December 14, 2021
The percentage of obese children and teens jumped from 19% pre-pandemic to 22%, and that could spell bad news for children's cardiovascular systems both now and down the line.

One in five future thyroid cancers linked to excess weight ... read more
December 9, 2021
The prevalence of obesity has doubled in Australia in the last two decades. As a result, overweight and obesity will likely be associated with 10,000 thyroid cancers in the next decade.

Glucose control is a key factor for reduced cancer risk in obesity and type 2 diabetes ... read more
December 6, 2021
Good glucose control is important for reduction of cancer risk in obesity and type 2 diabetes. Large durable weight loss, as such, appears to afford protection against cancer, but with good glucose control the number of cancer cases also drops radically, a new study shows.

Telehealth-delivered diet and exercise program eased knee pain and triggered weight loss ... read more
November 29, 2021
Combined diet and exercise Telehealth program saw 80 per cent of participants experience reduced knee pain with an average weight loss of approximately 10.2 per cent.

How obesity damages the skeletal muscle metabolism ... read more
November 29, 2021
A decline in metabolism and endurance of skeletal muscle is commonly observed in obese patients, but the underlying mechanism is not well-understood. A research team uncovers a new mechanism to explain how obesity jeopardizes the functions of skeletal muscle and provides a potential treatment against the disease.

Is the relationship between diet, intestinal bacteria and cells key to preventing systemic inflammation? ... read more
November 23, 2021
Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new study finds.

Deleting dysfunctional cells alleviates diabetes ... read more
November 22, 2021
Eliminating old, dysfunctional cells in human fat also alleviates signs of diabetes, researchers report. The discovery could lead to new treatments for Type 2 diabetes and other metabolic diseases.

New link between diet, intestinal stem cells and disease discovered ... read more
November 19, 2021
Obesity, diabetes and gastrointestinal cancer are frequently linked to an unhealthy diet. However, the molecular mechanisms responsible for this are not fully understood. Researchers have gained some new insights that help to better understand this connection. These findings provide an important basis for the development of non-invasive therapies.

Brief 5:2 diet advice is as effective as traditional GP advice, but people like it better, according to new study ... read more
November 17, 2021
A clinical trial has found people prefer receiving information on the 5:2 diet than standard GP weight management advice despite both interventions achieving similar modest weight loss results.

Arterial stiffness in adolescence may potentially cause hypertension and obesity in young adulthood ... read more
November 17, 2021
Arterial stiffness is a novel risk factor to be targeted for preventing and treating hypertension and obesity from a young age, a new study suggests.

Diet trumps drugs for anti-aging and good metabolic health ... read more
November 16, 2021
A study comparing the impact of diet versus drugs on the inner workings of our cells has found nutrition has a much stronger impact.

Obesity raises the risk of gum disease by inflating growth of bone-destroying cells ... read more
November 12, 2021
Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new research that sought to improve understanding of the connection between obesity and gum disease. The study, completed in an animal model and published in October in the Journal of Dental Research, found that excessive inflammation resulting from obesity raises the number of myeloid-derived suppressor cells (MDSC), a group of immune cells that increase during illness to regulate immune function. MDSCs, which originate in the bone marrow, develop into a range of different cell types, including osteoclasts (a cell that breaks down bone tissue).

A newly discovered genetic link to non-alcoholic inflammatory liver disease ... read more
November 10, 2021
Researchers have shown that albino mice of the C57BL/6 line are highly susceptible to developing the inflammatory liver condition non-alcoholic steatohepatitis (NASH) when fed a high cholesterol diet. The albino mice carry a mutation in the tyrosinase gene leading to a deficiency of melanin synthesis. NASH is a serious illness in humans, and the identification of the involvement of tyrosinase in NASH development will guide future research into this condition.

Fat-secreted molecule lowers response to common cancer treatment ... read more
November 9, 2021
Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study.

Galectin-1 linked to increased risk of type 2 diabetes ... read more
November 8, 2021
Researchers now associate elevated levels of the protein galectin-1 with increased risk of developing type 2 diabetes about 18 years later. At the same time, this protein seems to be a protective factor for the kidneys among type 2 diabetes patients at high risk for diabetic nephropathy.

Brain reveals the risk for developing obesity ... read more
November 3, 2021
Obesity risk factors of family background are associated with changes in the brain function, finds a new study. The results show that the function of neural networks regulating satiety and appetite is altered already before a person develops obesity.

One in 20 achieve remission from type 2 diabetes, Scottish study finds ... read more
November 2, 2021
Around one in 20 people in Scotland diagnosed with type 2 diabetes achieve remission from the disease, according to new research. This suggests people are achieving remission outside of research trials and without bariatric surgery.

Potential strategy for fighting obesity ... read more
November 2, 2021
Scientists may have identified a method of safely mimicking the weight-loss benefits of a plant compound that -- despite its harmful side effects -- hold critical answers to developing therapies for obesity.

The 5:2 diet: A good choice for gestational diabetes ... read more
November 1, 2021
Weight loss after gestational diabetes can prevent the onset of type 2 diabetes. Yet finding the most effective way to lose weight and keep it off can be a challenge, especially for mothers with a new baby. Now, new research suggests that the popular 5:2 or intermittent fasting diet is just as effective as a conventional energy-restricting diet, enabling women greater choice and flexibility when it comes to weight loss.

Sweet! How glycogen is linked to heat generation in fat cells ... read more
October 27, 2021
Researchers describe how energy expenditure and heat production are regulated in obesity through a previously unknown cellular pathway.

How diet affects tumors ... read more
October 20, 2021
Researchers analyzed ketogenic and calorically restricted diets in mice, revealing how those diets affect cancer cells and offering an explanation for why restricting calories may slow tumor growth.

Key protein linked to appetite and obesity in mice ... read more
October 15, 2021
Researchers have identified a protein that plays a key role in how the brain regulates appetite and metabolism. Loss of the protein, XRN1, from the forebrain, resulted in obese mice with an insatiable appetite, according to a new study.

How highly processed foods harm memory in the aging brain ... read more
October 14, 2021
Four weeks on a diet of highly processed food led to a strong inflammatory response in the brains of aging rats that was accompanied by behavioral signs of memory loss, a new study has found. Researchers also found that supplementing the processed diet with the omega-3 fatty acid DHA prevented memory problems and reduced the inflammatory effects almost entirely in older rats.

Scientists map brain circuit that drives activity in fertile females ... read more
October 14, 2021
Scientists have known for a century that female animals become more active just as they are about to ovulate, a behavior that evolved to enhance their chances of mating when they are fertile.

High BMI independently associated with death and longer ICU stay for COVID patients ... read more
October 13, 2021
In patients with COVID-19, a high body mass index (BMI) is associated with an increased risk of death and prolonged intensive care unit (ICU) stay, according to a new study.

Higher fasting ‘hunger hormone’ levels from healthy diet may improve heart health and metabolism ... read more
October 13, 2021
Fasting levels of the 'hunger hormone' ghrelin rebound after weight loss and can help reduce belly fat and improve the body's sensitivity to insulin, according to a new study.

Rye a better choice than wheat for weight loss ... read more
October 12, 2021
Eating whole grain rye products instead of refined wheat alternatives can offer worthwhile health benefits. Researchers recently published a study showing that people who ate high-fiber products made from whole grain rye lost more body fat and overall weight than those who ate corresponding products made from refined wheat.

Research review shows intermittent fasting works for weight loss, health changes ... read more
October 12, 2021
Intermittent fasting can produce clinically significant weight loss as well as improve metabolic health in individuals with obesity, according to a new study.

Is low-fat or whole-fat milk better for kids? Science says it makes no difference ... read more
October 12, 2021
A new study has found whole fat dairy is just as good for kids as low-fat.

A 'cousin' of Viagra reduces obesity by stimulating cells to burn fat ... read more
October 7, 2021
Researchers have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function -- without changes in food intake or daily activity.

Scientists discover 14 genes that cause obesity ... read more
October 1, 2021
The discovery of genes that directly cause obesity could pave the way for treatments for a condition that affects more than 40 percent of American adults.

Paradigm shift in treatment of type 2 diabetes to focus on weight loss ... read more
September 30, 2021
Medical researchers have reviewed current literature and are recommending a pivotal change in treatment of Type 2 diabetes to focus on obesity first and glucose control second.

How high-fat diets allow cancer cells to go unnoticed ... read more
September 28, 2021
The immune system relies on cell surface tags to recognize cancer cells. Researchers discovered mice who ate high-fat diets produced less of these tags on their intestinal cells, suppressing the ability of immune cells to identify and eliminate intestinal tumors. The high-fat diet also reduced the presence of certain bacteria in the mice's gut, which normally helps maintain the production of these tags.

Strength training can burn fat too, myth-busting study finds ... read more
September 22, 2021
A new systematic review and meta-analysis shows we can lose around 1.4 per cent of our entire body fat through strength training alone, which is similar to how much we might lose through cardio or aerobics.

Sticking to low-fat dairy may not be the only heart healthy option, study shows ... read more
September 21, 2021
New research amongst the world's biggest consumers of dairy foods has shown that those with higher intakes of dairy fat - measured by levels of fatty acids in the blood - had a lower risk of cardiovascular disease compared to those with low intakes. Higher intakes of dairy fat were not associated with an increased risk of death.

Eating less fat may save your hair ... read more
September 21, 2021
Researchers have uncovered a molecular mechanism behind why obesity can lead to hair thinning. They found that stem cells within hair follicles in mice given a high-fat diet behaved differently from those in mice with a standard diet. Inflammatory signals in the stem cells led to these differences, ultimately resulting in hair thinning and loss. These fascinating data shed light on the complicated link between obesity and organ dysfunction.

Researchers call for a focus on fitness over weight loss for obesity-related health conditions ... read more
September 20, 2021
The prevalence of obesity around the world has tripled over the past 40 years, and, along with that rise, dieting and attempts to lose weight also have soared. But according to a new article, when it comes to getting healthy and reducing mortality risk, increasing physical activity and improving fitness appear to be superior to weight loss. The authors say that employing a weight-neutral approach to the treatment of obesity-related health conditions also reduces the health risks associated with yo-yo dieting.

Meds, surgery may help obesity-related high blood pressure if diet, exercise fall short ... read more
September 20, 2021
Being overweight or having obesity, weight that is higher than what is considered healthy for an individual's height, is a major risk factor for high blood pressure. A healthy diet, more physical activity and less sedentary time are recommended to reduce blood pressure for people who are overweight or have obesity; however, evidence of long-term weight loss and sustained blood pressure reductions from these lifestyle changes is limited. New weight-loss medications and bariatric surgery have shown benefits in both long-term weight loss and improved blood pressure, which can reduce the long-term, negative impact of high blood pressure on organ damage.

More intensive and personalized strategies may be needed for weight loss ... read more
September 15, 2021
Modest weight loss can lead to meaningful risk reduction in adults with obesity. Although both behavioral economic incentives and environmental change strategies have shown promise for initial weight loss, to date their efficacy alone or in combination have not been compared.

Gut microbiota influences the ability to lose weight ... read more
September 14, 2021
Gut microbiota influences the ability to lose weight in humans, according to new research.

Scientists claim that overeating is not the primary cause of obesity ... read more
September 13, 2021
A perspective article challenges the 'energy balance model,' which says weight gain occurs because individuals consume more energy than they expend. According to the authors, 'conceptualizing obesity as a disorder of energy balance restates a principle of physics without considering the biological mechanisms underlying weight gain.' The authors argue for the 'carbohydrate insulin model,' which explains obesity as a metabolic disorder driven by what we eat, rather than how much. *Public health messaging exhorting people to eat less and exercise more has failed to stem rising rates of obesity and obesity-related diseases. *The energy balance model, which says weight gain is caused by consuming more energy than we expend, "restates a principle of physics without considering the biological mechanisms driving weight gain." *The carbohydrate-insulin model makes a bold claim: overeating doesn't cause obesity; the process of getting fat causes overeating. *The current obesity epidemic is due, in part, to hormonal responses to changes in food quality: in particular, high-glycemic load foods, which fundamentally change metabolism. *Focusing on what we eat rather than how much we eat is a better strategy for weight management.

Omics data suggests larger effect of smoking on body mass index than previously thought ... read more
September 9, 2021
Smoking-related DNA methylation patterns explain around a fifth of the variation in body mass index (BMI) between individuals, according to a new study.

Potential indicator for obesity risk detected during sleep ... read more
September 9, 2021
Researchers have shown that people with inflexible metabolisms burn less fat at night than those with flexible metabolism. The team measured the respiratory quotient throughout the night and found that despite equal ages, BMIs, and amount of fat, people with inflexible metabolisms burned more carbohydrates and less fat than did people with flexible metabolisms. The higher sleep-time quotient could be a previously unknown indicator for the risk of future metabolic disease.

Avocados change belly fat distribution in women, controlled study finds ... read more
September 7, 2021
An avocado a day could help redistribute belly fat in women toward a healthier profile, according to a new study. One hundred and five adults with overweight and obesity participated in a randomized controlled trial that provided one meal a day for 12 weeks. Women who consumed avocado as part of their daily meal had a reduction in deeper visceral abdominal fat.

High fat diets break the body clock in rats, and this might be the underlying cause of obesity ... read more
September 6, 2021
When rats are fed a high fat diet, this disturbs the body clock in their brain that normally controls satiety, leading to over-eating and obesity, according to new research.

Decades after toxic exposure, 9/11 first responders may still lower their risk of lung injury ... read more
September 2, 2021
A new study shows that losing weight and treating excess levels of fat in the blood may help prevent lung disease in those exposed to dangerous levels of fine particles from fire, smoke and toxic chemicals.

Study finds body mass index for children greatest in Midwest, least in West ... read more
September 1, 2021
A study examining the body mass index (BMI) of over 14,000 children from birth to age 15 shows those in the Midwest have the highest BMI levels while kids in the West have the lowest, suggesting regional influences may play a role in the development of childhood obesity.

School day structure could benefit children's health ... read more
September 1, 2021
Having a structured environment for children, whether during school days or when stuck in quarantine as the COVID-19 pandemic continues, could benefit children's health, according to new research.

How can I avoid heart disease or stroke? ... read more
August 30, 2021
As much as 90% of the risk of a heart attack, stroke, or peripheral arterial disease (PAD) can be explained by smoking, poor eating habits, lack of physical activity, abdominal obesity, high blood pressure, raised blood lipid levels, diabetes, psychosocial factors, or alcohol. These guidelines focus on atherosclerotic cardiovascular disease (CVD), which affects the arteries. As the inside of the arteries become clogged up by fatty deposits, they can no longer supply enough blood to the body. This process is the main cause of heart attacks, strokes, PAD and sudden death where arteries become completely blocked. The most important way to prevent these conditions is to adopt a healthy lifestyle throughout life, especially not smoking, and to treat risk factors.

Eating walnuts daily lowered 'bad' cholesterol and may reduce cardiovascular disease risk ... read more
August 30, 2021
Healthy older adults who ate a handful of walnuts (about ½ cup) a day for two years modestly lowered their level of low-density lipoprotein or LDL cholesterol levels. Consuming walnuts daily also reduced the number of LDL particles, a predictor of cardiovascular disease risk. The study explored the effects of a walnut-enriched diet on overall cholesterol in elderly individuals from diverse geographical locations and spanning two years.

Common pesticide may contribute to global obesity crisis ... read more
August 27, 2021
Researchers discovered that chlorpyrifos, which is banned for use on foods in Canada but widely sprayed on fruits and vegetables in many other parts of the world, slows down the burning of calories in the brown adipose tissue of mice. Reducing this burning of calories, a process known as diet-induced thermogenesis, causes the body to store these extra calories, promoting obesity. Scientists made the discovery after studying 34 commonly used pesticides and herbicides in brown fat cells and testing the effects of chlorpyrifos in mice fed high calorie diets.

Large genetic analysis identifies numerous gene variants linked with differences in food intake ... read more
August 24, 2021
A team of researchers have identified more than two dozen genetic regions that may affect individuals' food intake.

 


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